Michael Jeffrey Gandal

Title(s)Assistant Adjunct Professor, Psychiatry and Biobehavioral Sciences
SchoolMedicine
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    Title(s)Assistant Adjunct Professor, Human Genetics


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    1. Single-cell genomics and regulatory networks for 388 human brains. bioRxiv. 2024 Mar 30. Emani PS, Liu JJ, Clarke D, Jensen M, Warrell J, Gupta C, Meng R, Lee CY, Xu S, Dursun C, Lou S, Chen Y, Chu Z, Galeev T, Hwang A, Li Y, Ni P, Zhou X, PsychENCODE Consortium, Bakken TE, Bendl J, Bicks L, Chatterjee T, Cheng L, Cheng Y, Dai Y, Duan Z, Flaherty M, Fullard JF, Gancz M, Garrido-Martín D, Gaynor-Gillett S, Grundman J, Hawken N, Henry E, Hoffman GE, Huang A, Jiang Y, Jin T, Jorstad NL, Kawaguchi R, Khullar S, Liu J, Liu J, Liu S, Ma S, Margolis M, Mazariegos S, Moore J, Moran JR, Nguyen E, Phalke N, Pjanic M, Pratt H, Quintero D, Rajagopalan AS, Riesenmy TR, Shedd N, Shi M, Spector M, Terwilliger R, Travaglini KJ, Wamsley B, Wang G, Xia Y, Xiao S, Yang AC, Zheng S, Gandal MJ, Lee D, Lein ES, Roussos P, Sestan N, Weng Z, White KP, Won H, Girgenti MJ, Zhang J, Wang D, Geschwind D, Gerstein M. PMID: 38562822; PMCID: PMC10983939.
      View in: PubMed   Mentions:
    2. Isoform-level transcriptome-wide association uncovers genetic risk mechanisms for neuropsychiatric disorders in the human brain. Nat Genet. 2023 Dec; 55(12):2117-2128. Bhattacharya A, Vo DD, Jops C, Kim M, Wen C, Hervoso JL, Pasaniuc B, Gandal MJ. PMID: 38036788; PMCID: PMC10703692.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    3. Multi-ancestry genome-wide association study of cannabis use disorder yields insight into disease biology and public health implications. Nat Genet. 2023 Dec; 55(12):2094-2103. Levey DF, Galimberti M, Deak JD, Wendt FR, Bhattacharya A, Koller D, Harrington KM, Quaden R, Johnson EC, Gupta P, Biradar M, Lam M, Cooke M, Rajagopal VM, Empke SLL, Zhou H, Nunez YZ, Kranzler HR, Edenberg HJ, Agrawal A, Smoller JW, Lencz T, Hougaard DM, Børglum AD, Demontis D, Veterans Affairs Million Veteran Program, Gaziano JM, Gandal MJ, Polimanti R, Stein MB, Gelernter J. PMID: 37985822; PMCID: PMC10703690.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    4. The molecular genetic landscape of human brain size variation. Cell Rep. 2023 11 28; 42(11):113439. Seidlitz J, Mallard TT, Vogel JW, Lee YH, Warrier V, Ball G, Hansson O, Hernandez LM, Mandal AS, Wagstyl K, Lombardo MV, Courchesne E, Glessner JT, Satterthwaite TD, Bethlehem RAI, Bernstock JD, Lifespan Brain Chart Consortium, Tasaki S, Ng B, Gaiteri C, Smoller JW, Ge T, Gur RE, Gandal MJ, Alexander-Bloch AF. PMID: 37963017.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    5. Comparison of gene expression in living and postmortem human brain. medRxiv. 2023 Nov 09. Collado-Torres L, Klei L, Liu C, Kleinman JE, Hyde TM, Geschwind DH, Gandal MJ, Devlin B, Weinberger DR. PMID: 37986747; PMCID: PMC10659492.
      View in: PubMed   Mentions:
    6. Developmental isoform diversity in the human neocortex informs neuropsychiatric risk mechanisms. bioRxiv. 2023 Oct 11. Patowary A, Zhang P, Jops C, Vuong CK, Ge X, Hou K, Kim M, Gong N, Margolis M, Vo D, Wang X, Liu C, Pasaniuc B, Li JJ, Gandal MJ, de la Torre-Ubieta L. PMID: 36993726; PMCID: PMC10055310.
      View in: PubMed   Mentions:
    7. GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors. Am J Psychiatry. 2023 10 01; 180(10):723-738. Docherty AR, Mullins N, Ashley-Koch AE, Qin X, Coleman JRI, Shabalin A, Kang J, Murnyak B, Wendt F, Adams M, Campos AI, DiBlasi E, Fullerton JM, Kranzler HR, Bakian AV, Monson ET, Rentería ME, Walss-Bass C, Andreassen OA, Behera C, Bulik CM, Edenberg HJ, Kessler RC, Mann JJ, Nurnberger JI, Pistis G, Streit F, Ursano RJ, Polimanti R, Dennis M, Garrett M, Hair L, Harvey P, Hauser ER, Hauser MA, Huffman J, Jacobson D, Madduri R, McMahon B, Oslin DW, Trafton J, Awasthi S, Berrettini WH, Bohus M, Chang X, Chen HC, Chen WJ, Christensen ED, Crow S, Duriez P, Edwards AC, Fernández-Aranda F, Galfalvy H, Gandal M, Gorwood P, Guo Y, Hafferty JD, Hakonarson H, Halmi KA, Hishimoto A, Jain S, Jamain S, Jiménez-Murcia S, Johnson C, Kaplan AS, Kaye WH, Keel PK, Kennedy JL, Kim M, Klump KL, Levey DF, Li D, Liao SC, Lieb K, Lilenfeld L, Marshall CR, Mitchell JE, Okazaki S, Otsuka I, Pinto D, Powers A, Ramoz N, Ripke S, Roepke S, Rozanov V, Scherer SW, Schmahl C, Sokolowski M, Starnawska A, Strober M, Su MH, Thornton LM, Treasure J, Ware EB, Watson HJ, Witt SH, Woodside DB, Yilmaz Z, Zillich L, Adolfsson R, Agartz I, Alda M, Alfredsson L, Appadurai V, Artigas MS, Van der Auwera S, Azevedo MH, Bass N, Bau CHD, Baune BT, Bellivier F, Berger K, Biernacka JM, Bigdeli TB, Binder EB, Boehnke M, Boks MP, Braff DL, Bryant R, Budde M, Byrne EM, Cahn W, Castelao E, Cervilla JA, Chaumette B, Corvin A, Craddock N, Djurovic S, Foo JC, Forstner AJ, Frye M, Gatt JM, Giegling I, Grabe HJ, Green MJ, Grevet EH, Grigoroiu-Serbanescu M, Gutierrez B, Guzman-Parra J, Hamshere ML, Hartmann AM, Hauser J, Heilmann-Heimbach S, Hoffmann P, Ising M, Jones I, Jones LA, Jonsson L, Kahn RS, Kelsoe JR, Kendler KS, Kloiber S, Koenen KC, Kogevinas M, Krebs MO, Landén M, Leboyer M, Lee PH, Levinson DF, Liao C, Lissowska J, Mayoral F, McElroy SL, McGrath P, McGuffin P, McQuillin A, Mehta D, Melle I, Mitchell PB, Molina E, Morken G, Nievergelt C, Nöthen MM, O'Donovan MC, Ophoff RA, Owen MJ, Pato C, Pato MT, Penninx BWJH, Potash JB, Power RA, Preisig M, Quested D, Ramos-Quiroga JA, Reif A, Ribasés M, Richarte V, Rietschel M, Rivera M, Roberts A, Roberts G, Rouleau GA, Rovaris DL, Sanders AR, Schofield PR, Schulze TG, Scott LJ, Serretti A, Shi J, Sirignano L, Sklar P, Smeland OB, Smoller JW, Sonuga-Barke EJS, Trzaskowski M, Tsuang MT, Turecki G, Vilar-Ribó L, Vincent JB, Völzke H, Walters JTR, Weickert CS, Weickert TW, Weissman MM, Williams LM, Wray NR, Zai CC, Agerbo E, Børglum AD, Breen G, Demontis D, Erlangsen A, Gelernter J, Glatt SJ, Hougaard DM, Hwu HG, Kuo PH, Lewis CM, Li QS, Liu CM, Martin NG, McIntosh AM, Medland SE, Mors O, Nordentoft M, Olsen CM, Porteous D, Smith DJ, Stahl EA, Stein MB, Wasserman D, Werge T, Whiteman DC, Willour V, VA Million Veteran Program (MVP), MVP Suicide Exemplar Workgroup, Suicide Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Eating Disorder Working Group of the Psychiatric Genomics Consortium, German Borderline Genomics Consortium, Coon H, Beckham JC, Kimbrel NA, Ruderfer DM. PMID: 37777856; PMCID: PMC10603363.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    8. Genetic insights into human cortical organization and development through genome-wide analyses of 2,347 neuroimaging phenotypes. Nat Genet. 2023 09; 55(9):1483-1493. Warrier V, Stauffer EM, Huang QQ, Wigdor EM, Slob EAW, Seidlitz J, Ronan L, Valk SL, Mallard TT, Grotzinger AD, Romero-Garcia R, Baron-Cohen S, Geschwind DH, Lancaster MA, Murray GK, Gandal MJ, Alexander-Bloch A, Won H, Martin HC, Bullmore ET, Bethlehem RAI. PMID: 37592024; PMCID: PMC10600728.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    9. Improvement of sensory deficits in fragile X mice by increasing cortical interneuron activity after the critical period. Neuron. 2023 09 20; 111(18):2863-2880.e6. Kourdougli N, Suresh A, Liu B, Juarez P, Lin A, Chung DT, Graven Sams A, Gandal MJ, Martínez-Cerdeño V, Buonomano DV, Hall BJ, Mombereau C, Portera-Cailliau C. PMID: 37451263; PMCID: PMC10529373.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    10. 150 risk variants for diverticular disease of intestine prioritize cell types and enable polygenic prediction of disease susceptibility. Cell Genom. 2023 Jul 12; 3(7):100326. Wu Y, Goleva SB, Breidenbach LB, Kim M, MacGregor S, Gandal MJ, Davis LK, Wray NR. PMID: 37492107; PMCID: PMC10363821.
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    11. No Increased Detection of Nucleic Acids of CNS-related Viruses in the Brains of Patients with Schizophrenia, Bipolar Disorder, and Autism Spectrum Disorder. Schizophr Bull. 2023 05 03; 49(3):551-558. Min S, Gandal MJ, Kopp RF, Liu C, Chen C. PMID: 36857101; PMCID: PMC10154715.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    12. Interactions between the lipidome and genetic and environmental factors in autism. Nat Med. 2023 04; 29(4):936-949. Yap CX, Henders AK, Alvares GA, Giles C, Huynh K, Nguyen A, Wallace L, McLaren T, Yang Y, Hernandez LM, Gandal MJ, Hansell NK, Cleary D, Grove R, Hafekost C, Harun A, Holdsworth H, Jellett R, Khan F, Lawson LP, Leslie J, Levis Frenk M, Masi A, Mathew NE, Muniandy M, Nothard M, Miller JL, Nunn L, Strike LT, Cadby G, Moses EK, Busselton Health Study Investigators, de Zubicaray GI, Thompson PM, McMahon KL, Wright MJ, Visscher PM, Dawson PA, Dissanayake C, Eapen V, Heussler HS, Whitehouse AJO, Meikle PJ, Wray NR, Gratten J. PMID: 37076741; PMCID: PMC10115648.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    13. Multi-ancestry phenome-wide association of complement component 4 variation with psychiatric and brain phenotypes in youth. Genome Biol. 2023 03 07; 24(1):42. Hernandez LM, Kim M, Zhang P, Bethlehem RAI, Hoftman G, Loughnan R, Smith D, Bookheimer SY, Fan CC, Bearden CE, Thompson WK, Gandal MJ. PMID: 36882872; PMCID: PMC9990244.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    14. Cross-ancestry, cell-type-informed atlas of gene, isoform, and splicing regulation in the developing human brain. medRxiv. 2023 Mar 06. Wen C, Margolis M, Dai R, Zhang P, Przytycki PF, Vo DD, Bhattacharya A, Matoba N, Jiao C, Kim M, Tsai E, Hoh C, Aygün N, Walker RL, Chatzinakos C, Clarke D, Pratt H, Consortium P, Peters MA, Gerstein M, Daskalakis NP, Weng Z, Jaffe AE, Kleinman JE, Hyde TM, Weinberger DR, Bray NJ, Sestan N, Geschwind DH, Roeder K, Gusev A, Pasaniuc B, Stein JL, Love MI, Pollard KS, Liu C, Gandal MJ. PMID: 36945630; PMCID: PMC10029021.
      View in: PubMed   Mentions:
    15. Neuron-specific transcriptomic signatures indicate neuroinflammation and altered neuronal activity in ASD temporal cortex. Proc Natl Acad Sci U S A. 2023 03 07; 120(10):e2206758120. Zhang P, Omanska A, Ander BP, Gandal MJ, Stamova B, Schumann CM. PMID: 36862688; PMCID: PMC10013873.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    16. GeneticsMakie.jl: a versatile and scalable toolkit for visualizing locus-level genetic and genomic data. Bioinformatics. 2023 01 01; 39(1). Kim M, Vo DD, Kumagai ME, Jops CT, Gandal MJ. PMID: 36495218; PMCID: PMC9825774.
      View in: PubMed   Mentions: 1     Fields:    
    17. Broad transcriptomic dysregulation occurs across the cerebral cortex in ASD. Nature. 2022 Nov; 611(7936):532-539. Gandal MJ, Haney JR, Wamsley B, Yap CX, Parhami S, Emani PS, Chang N, Chen GT, Hoftman GD, de Alba D, Ramaswami G, Hartl CL, Bhattacharya A, Luo C, Jin T, Wang D, Kawaguchi R, Quintero D, Ou J, Wu YE, Parikshak NN, Swarup V, Belgard TG, Gerstein M, Pasaniuc B, Geschwind DH. PMID: 36323788; PMCID: PMC9668748.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    18. A Critical Appraisal of Imaging Transcriptomics. Biol Psychiatry Glob Open Sci. 2022 Oct; 2(4):311-313. Mandal AS, Gandal M, Seidlitz J, Alexander-Bloch A. PMID: 36324661; PMCID: PMC9616265.
      View in: PubMed   Mentions:
    19. TGFβ superfamily signaling regulates the state of human stem cell pluripotency and capacity to create well-structured telencephalic organoids. Stem Cell Reports. 2022 10 11; 17(10):2220-2238. Watanabe M, Buth JE, Haney JR, Vishlaghi N, Turcios F, Elahi LS, Gu W, Pearson CA, Kurdian A, Baliaouri NV, Collier AJ, Miranda OA, Dunn N, Chen D, Sabri S, Torre-Ubieta L, Clark AT, Plath K, Christofk HR, Kornblum HI, Gandal MJ, Novitch BG. PMID: 36179695; PMCID: PMC9561534.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    20. White matter microstructure shows sex differences in late childhood: Evidence from 6797 children. Hum Brain Mapp. 2023 02 01; 44(2):535-548. Lawrence KE, Abaryan Z, Laltoo E, Hernandez LM, Gandal MJ, McCracken JT, Thompson PM. PMID: 36177528; PMCID: PMC9842921.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    21. Comment on: What genes are differentially expressed in individuals with schizophrenia? A systematic review. Mol Psychiatry. 2023 02; 28(2):523-525. Hoffman GE, Jaffe AE, Gandal MJ, Collado-Torres L, Sieberts SK, Devlin B, Geschwind DH, Weinberger DR, Roussos P. PMID: 36123423; PMCID: PMC10035364.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    22. Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data. Nat Genet. 2022 10; 54(10):1572-1580. Zhang MJ, Hou K, Dey KK, Sakaue S, Jagadeesh KA, Weinand K, Taychameekiatchai A, Rao P, Pisco AO, Zou J, Wang B, Gandal M, Raychaudhuri S, Pasaniuc B, Price AL. PMID: 36050550; PMCID: PMC9891382.
      View in: PubMed   Mentions: 25     Fields:    
    23. Association between resting-state functional brain connectivity and gene expression is altered in autism spectrum disorder. Nat Commun. 2022 06 09; 13(1):3328. Berto S, Treacher AH, Caglayan E, Luo D, Haney JR, Gandal MJ, Geschwind DH, Montillo AA, Konopka G. PMID: 35680911; PMCID: PMC9184501.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    24. Mapping genomic loci implicates genes and synaptic biology in schizophrenia. Nature. 2022 04; 604(7906):502-508. Trubetskoy V, Pardiñas AF, Qi T, Panagiotaropoulou G, Awasthi S, Bigdeli TB, Bryois J, Chen CY, Dennison CA, Hall LS, Lam M, Watanabe K, Frei O, Ge T, Harwood JC, Koopmans F, Magnusson S, Richards AL, Sidorenko J, Wu Y, Zeng J, Grove J, Kim M, Li Z, Voloudakis G, Zhang W, Adams M, Agartz I, Atkinson EG, Agerbo E, Al Eissa M, Albus M, Alexander M, Alizadeh BZ, Alptekin K, Als TD, Amin F, Arolt V, Arrojo M, Athanasiu L, Azevedo MH, Bacanu SA, Bass NJ, Begemann M, Belliveau RA, Bene J, Benyamin B, Bergen SE, Blasi G, Bobes J, Bonassi S, Braun A, Bressan RA, Bromet EJ, Bruggeman R, Buckley PF, Buckner RL, Bybjerg-Grauholm J, Cahn W, Cairns MJ, Calkins ME, Carr VJ, Castle D, Catts SV, Chambert KD, Chan RCK, Chaumette B, Cheng W, Cheung EFC, Chong SA, Cohen D, Consoli A, Cordeiro Q, Costas J, Curtis C, Davidson M, Davis KL, de Haan L, Degenhardt F, DeLisi LE, Demontis D, Dickerson F, Dikeos D, Dinan T, Djurovic S, Duan J, Ducci G, Dudbridge F, Eriksson JG, Fañanás L, Faraone SV, Fiorentino A, Forstner A, Frank J, Freimer NB, Fromer M, Frustaci A, Gadelha A, Genovese G, Gershon ES, Giannitelli M, Giegling I, Giusti-Rodríguez P, Godard S, Goldstein JI, González Peñas J, González-Pinto A, Gopal S, Gratten J, Green MF, Greenwood TA, Guillin O, Gülöksüz S, Gur RE, Gur RC, Gutiérrez B, Hahn E, Hakonarson H, Haroutunian V, Hartmann AM, Harvey C, Hayward C, Henskens FA, Herms S, Hoffmann P, Howrigan DP, Ikeda M, Iyegbe C, Joa I, Julià A, Kähler AK, Kam-Thong T, Kamatani Y, Karachanak-Yankova S, Kebir O, Keller MC, Kelly BJ, Khrunin A, Kim SW, Klovins J, Kondratiev N, Konte B, Kraft J, Kubo M, Kucinskas V, Kucinskiene ZA, Kusumawardhani A, Kuzelova-Ptackova H, Landi S, Lazzeroni LC, Lee PH, Legge SE, Lehrer DS, Lencer R, Lerer B, Li M, Lieberman J, Light GA, Limborska S, Liu CM, Lönnqvist J, Loughland CM, Lubinski J, Luykx JJ, Lynham A, Macek M, Mackinnon A, Magnusson PKE, Maher BS, Maier W, Malaspina D, Mallet J, Marder SR, Marsal S, Martin AR, Martorell L, Mattheisen M, McCarley RW, McDonald C, McGrath JJ, Medeiros H, Meier S, Melegh B, Melle I, Mesholam-Gately RI, Metspalu A, Michie PT, Milani L, Milanova V, Mitjans M, Molden E, Molina E, Molto MD, Mondelli V, Moreno C, Morley CP, Muntané G, Murphy KC, Myin-Germeys I, Nenadic I, Nestadt G, Nikitina-Zake L, Noto C, Nuechterlein KH, O'Brien NL, O'Neill FA, Oh SY, Olincy A, Ota VK, Pantelis C, Papadimitriou GN, Parellada M, Paunio T, Pellegrino R, Periyasamy S, Perkins DO, Pfuhlmann B, Pietiläinen O, Pimm J, Porteous D, Powell J, Quattrone D, Quested D, Radant AD, Rampino A, Rapaport MH, Rautanen A, Reichenberg A, Roe C, Roffman JL, Roth J, Rothermundt M, Rutten BPF, Saker-Delye S, Salomaa V, Sanjuan J, Santoro ML, Savitz A, Schall U, Scott RJ, Seidman LJ, Sharp SI, Shi J, Siever LJ, Sigurdsson E, Sim K, Skarabis N, Slominsky P, So HC, Sobell JL, Söderman E, Stain HJ, Steen NE, Steixner-Kumar AA, Stögmann E, Stone WS, Straub RE, Streit F, Strengman E, Stroup TS, Subramaniam M, Sugar CA, Suvisaari J, Svrakic DM, Swerdlow NR, Szatkiewicz JP, Ta TMT, Takahashi A, Terao C, Thibaut F, Toncheva D, Tooney PA, Torretta S, Tosato S, Tura GB, Turetsky BI, Üçok A, Vaaler A, van Amelsvoort T, van Winkel R, Veijola J, Waddington J, Walter H, Waterreus A, Webb BT, Weiser M, Williams NM, Witt SH, Wormley BK, Wu JQ, Xu Z, Yolken R, Zai CC, Zhou W, Zhu F, Zimprich F, Atbasoglu EC, Ayub M, Benner C, Bertolino A, Black DW, Bray NJ, Breen G, Buccola NG, et al. PMID: 35396580; PMCID: PMC9392466.
      View in: PubMed   Mentions: 460     Fields:    Translation:Humans
    25. Decoupling Sleep and Brain Size in Childhood: An Investigation of Genetic Covariation in the Adolescent Brain Cognitive Development Study. Biol Psychiatry Glob Open Sci. 2023 Jan; 3(1):139-148. Hernandez LM, Kim M, Hernandez C, Thompson W, Fan CC, Galván A, Dapretto M, Bookheimer SY, Fuligni A, Gandal MJ. PMID: 36712562; PMCID: PMC9874135.
      View in: PubMed   Mentions: 1  
    26. Human Astrocytes Exhibit Tumor Microenvironment-, Age-, and Sex-Related Transcriptomic Signatures. J Neurosci. 2022 02 23; 42(8):1587-1603. Krawczyk MC, Haney JR, Pan L, Caneda C, Khankan RR, Reyes SD, Chang JW, Morselli M, Vinters HV, Wang AC, Cobos I, Gandal MJ, Bergsneider M, Kim W, Liau LM, Yong W, Jalali A, Deneen B, Grant GA, Mathern GW, Fallah A, Zhang Y. PMID: 34987109; PMCID: PMC8883850.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    27. Associations between patterns in comorbid diagnostic trajectories of individuals with schizophrenia and etiological factors. Nat Commun. 2021 11 16; 12(1):6617. Krebs MD, Themudo GE, Benros ME, Mors O, Børglum AD, Hougaard D, Mortensen PB, Nordentoft M, Gandal MJ, Fan CC, Geschwind DH, Schork AJ, Werge T, Thompson WK. PMID: 34785645; PMCID: PMC8595374.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    28. Full-length transcript sequencing of human and mouse cerebral cortex identifies widespread isoform diversity and alternative splicing. Cell Rep. 2021 11 16; 37(7):110022. Leung SK, Jeffries AR, Castanho I, Jordan BT, Moore K, Davies JP, Dempster EL, Bray NJ, O'Neill P, Tseng E, Ahmed Z, Collier DA, Jeffery ED, Prabhakar S, Schalkwyk L, Jops C, Gandal MJ, Sheynkman GM, Hannon E, Mill J. PMID: 34788620; PMCID: PMC8609283.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    29. Maternal Immune Activation during Pregnancy Alters Postnatal Brain Growth and Cognitive Development in Nonhuman Primate Offspring. J Neurosci. 2021 12 01; 41(48):9971-9987. Vlasova RM, Iosif AM, Ryan AM, Funk LH, Murai T, Chen S, Lesh TA, Rowland DJ, Bennett J, Hogrefe CE, Maddock RJ, Gandal MJ, Geschwind DH, Schumann CM, Van de Water J, McAllister AK, Carter CS, Styner MA, Amaral DG, Bauman MD. PMID: 34607967; PMCID: PMC8638691.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    30. Postnatal immune activation causes social deficits in a mouse model of tuberous sclerosis: Role of microglia and clinical implications. Sci Adv. 2021 Sep 17; 7(38):eabf2073. López-Aranda MF, Chattopadhyay I, Boxx GM, Fraley ER, Silva TK, Zhou M, Phan M, Herrera I, Taloma S, Mandanas R, Bach K, Gandal M, Geschwind DH, Cheng G, Rzhetsky A, White SA, Silva AJ. PMID: 34533985; PMCID: PMC8448451.
      View in: PubMed   Mentions: 8     Fields:    
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    68. Pyramidal cell selective ablation of N-methyl-D-aspartate receptor 1 causes increase in cellular and network excitability. Biol Psychiatry. 2015 Mar 15; 77(6):556-68. Tatard-Leitman VM, Jutzeler CR, Suh J, Saunders JA, Billingslea EN, Morita S, White R, Featherstone RE, Ray R, Ortinski PI, Banerjee A, Gandal MJ, Lin R, Alexandrescu A, Liang Y, Gur RE, Borgmann-Winter KE, Carlson GC, Hahn CG, Siegel SJ. PMID: 25156700; PMCID: PMC4297754.
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    69. Parvalbumin cell ablation of NMDA-R1 causes increased resting network excitability with associated social and self-care deficits. Neuropsychopharmacology. 2014 Jun; 39(7):1603-13. Billingslea EN, Tatard-Leitman VM, Anguiano J, Jutzeler CR, Suh J, Saunders JA, Morita S, Featherstone RE, Ortinski PI, Gandal MJ, Lin R, Liang Y, Gur RE, Carlson GC, Hahn CG, Siegel SJ. PMID: 24525709; PMCID: PMC4023157.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    70. Measuring the maturity of the fast-spiking interneuron transcriptional program in autism, schizophrenia, and bipolar disorder. PLoS One. 2012; 7(8):e41215. Gandal MJ, Nesbitt AM, McCurdy RM, Alter MD. PMID: 22936973; PMCID: PMC3427326.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    71. Mice with reduced NMDA receptor expression: more consistent with autism than schizophrenia? Genes Brain Behav. 2012 Aug; 11(6):740-50. Gandal MJ, Anderson RL, Billingslea EN, Carlson GC, Roberts TP, Siegel SJ. PMID: 22726567; PMCID: PMC3808979.
      View in: PubMed   Mentions: 58     Fields:    Translation:Animals
    72. GABAB-mediated rescue of altered excitatory-inhibitory balance, gamma synchrony and behavioral deficits following constitutive NMDAR-hypofunction. Transl Psychiatry. 2012 Jul 17; 2:e142. Gandal MJ, Sisti J, Klook K, Ortinski PI, Leitman V, Liang Y, Thieu T, Anderson R, Pierce RC, Jonak G, Gur RE, Carlson G, Siegel SJ. PMID: 22806213; PMCID: PMC3410621.
      View in: PubMed   Mentions: 100     Fields:    Translation:AnimalsCells
    73. NMDA antagonist MK801 recreates auditory electrophysiology disruption present in autism and other neurodevelopmental disorders. Behav Brain Res. 2012 Oct 01; 234(2):233-7. Saunders JA, Gandal MJ, Roberts TP, Siegel SJ. PMID: 22771812; PMCID: PMC4124897.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    74. Nicotine normalizes event related potentials in COMT-Val-tg mice and increases gamma and theta spectral density. Behav Neurosci. 2012 Apr; 126(2):332-43. Cao YA, Featherstone RE, Gandal MJ, Liang Y, Jutzeler C, Saunders J, Tatard-Leitman V, Chen J, Weinberger DR, Lerman C, Siegel SJ. PMID: 22309446.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    75. NMDA antagonists recreate signal-to-noise ratio and timing perturbations present in schizophrenia. Neurobiol Dis. 2012 Apr; 46(1):93-100. Saunders JA, Gandal MJ, Siegel SJ. PMID: 22245663; PMCID: PMC4161042.
      View in: PubMed   Mentions: 38     Fields:    Translation:Animals
    76. MeCP2+/- mouse model of RTT reproduces auditory phenotypes associated with Rett syndrome and replicate select EEG endophenotypes of autism spectrum disorder. Neurobiol Dis. 2012 Apr; 46(1):88-92. Liao W, Gandal MJ, Ehrlichman RS, Siegel SJ, Carlson GC. PMID: 22249109; PMCID: PMC3299908.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimals
    77. mGluR5-antagonist mediated reversal of elevated stereotyped, repetitive behaviors in the VPA model of autism. PLoS One. 2011; 6(10):e26077. Mehta MV, Gandal MJ, Siegel SJ. PMID: 22016815; PMCID: PMC3189241.
      View in: PubMed   Mentions: 73     Fields:    Translation:Animals
    78. Dysbindin-1 mutant mice implicate reduced fast-phasic inhibition as a final common disease mechanism in schizophrenia. Proc Natl Acad Sci U S A. 2011 Oct 25; 108(43):E962-70. Carlson GC, Talbot K, Halene TB, Gandal MJ, Kazi HA, Schlosser L, Phung QH, Gur RE, Arnold SE, Siegel SJ. PMID: 21969553; PMCID: PMC3203764.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    79. Gamma synchrony: towards a translational biomarker for the treatment-resistant symptoms of schizophrenia. Neuropharmacology. 2012 Mar; 62(3):1504-18. Gandal MJ, Edgar JC, Klook K, Siegel SJ. PMID: 21349276; PMCID: PMC3264822.
      View in: PubMed   Mentions: 138     Fields:    Translation:HumansAnimals
    80. Validating γ oscillations and delayed auditory responses as translational biomarkers of autism. Biol Psychiatry. 2010 Dec 15; 68(12):1100-6. Gandal MJ, Edgar JC, Ehrlichman RS, Mehta M, Roberts TP, Siegel SJ. PMID: 21130222; PMCID: PMC5070466.
      View in: PubMed   Mentions: 156     Fields:    Translation:HumansAnimals
    81. Ketamine modulates theta and gamma oscillations. J Cogn Neurosci. 2010 Jul; 22(7):1452-64. Lazarewicz MT, Ehrlichman RS, Maxwell CR, Gandal MJ, Finkel LH, Siegel SJ. PMID: 19583475.
      View in: PubMed   Mentions: 109     Fields:    Translation:Animals
    82. Mouse behavioral endophenotypes for schizophrenia. Brain Res Bull. 2010 Sep 30; 83(3-4):147-61. Amann LC, Gandal MJ, Halene TB, Ehrlichman RS, White SL, McCarren HS, Siegel SJ. PMID: 20433908.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimals
    83. In vitro-in vivo correlations of scalable PLGA-risperidone implants for the treatment of schizophrenia. Pharm Res. 2010 Aug; 27(8):1730-7. Amann LC, Gandal MJ, Lin R, Liang Y, Siegel SJ. PMID: 20422263.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimals
    84. N-methyl-d-aspartic acid receptor antagonist-induced frequency oscillations in mice recreate pattern of electrophysiological deficits in schizophrenia. Neuroscience. 2009 Jan 23; 158(2):705-12. Ehrlichman RS, Gandal MJ, Maxwell CR, Lazarewicz MT, Finkel LH, Contreras D, Turetsky BI, Siegel SJ. PMID: 19015010.
      View in: PubMed   Mentions: 88     Fields:    Translation:Animals
    85. A novel electrophysiological model of chemotherapy-induced cognitive impairments in mice. Neuroscience. 2008 Nov 11; 157(1):95-104. Gandal MJ, Ehrlichman RS, Rudnick ND, Siegel SJ. PMID: 18835334; PMCID: PMC2715916.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    86. Deletion of vanilloid receptor 1-expressing primary afferent neurons for pain control. J Clin Invest. 2004 May; 113(9):1344-52. Karai L, Brown DC, Mannes AJ, Connelly ST, Brown J, Gandal M, Wellisch OM, Neubert JK, Olah Z, Iadarola MJ. PMID: 15124026; PMCID: PMC398431.
      View in: PubMed   Mentions: 152     Fields:    Translation:HumansAnimalsCells
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