CSORDA, a NIDA-funded P50 Center at UCLA with support from the UCLA CTSI, invites applications for the 2020-2021 academic year. This call is the second of 3 annual calls for pilot funding in the CSORDA P50 pilot program. Funding is available for high-quality, innovative research that is in opioid-related areas and of relevance to the CSORDA mission. Any approach, from basic to preclinical or clinical research that involves exogenous or endogenous opioid actions, will be considered. Engagement of CSORDA UCLA Cores is encouraged.Up to $20,000/year is available (or $40,000/year with justified clinical translational significance). Four pilot projects will be funded in 2020. Up to two of them will be considered at the $40,000 funding level if strongly justified.