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Researchers Map Genetic ‘Switches’ Behind Human Brain Evolution



UCLA CTSI News Archive

UCLA Health

Daniel Geschwind, M.D.

UCLA researchers have developed the first map of gene regulation in human neurogenesis, the process by which neural stem cells turn into brain cells and the cerebral cortex expands in size. The scientists identified factors that govern the growth of our brains and, in some cases, set the stage for several brain disorders that appear later in life.

The study's senior author is Daniel Geschwind, the Gordon and Virginia MacDonald Distinguished Chair in Human Genetics and professor of Neurology and Psychiatry at the UCLA School of Medicine. Geschwind is director of the Neurogenetics Program and the Center for Autism Research and Treatment (CART), co-director of the Center for Neurobehavioral Genetics, and Program Leader for the Precision Medicine Program for UCLA CTSI.

See the UCLA press release for details. The research appears in the Jan. 11, 2018 edition of Cell.