Network Capacity
The Network Capacity (NC) component of the UCLA CTSI provides the infrastructure for participation in national collaborations while contributing to the transformation of the conduct of multisite clinical trials. We are participating in the Trial Innovation Network (TIN), the Trial Innovation Centers (TICs) and the Recruitment Innovation Center (RIC). We match investigator expertise with trial opportunities and refer hub researchers to TIN network services and consultations. Our team guides proposal submission through the TIN website. We participate in NIH initiatives to improve both study activation and enrollment.
Partnerships and notable achievements include: (1) harmonizing network institutional review board (IRB) reviews (e.g., with Vanderbilt University, University of Utah, and Johns Hopkins University), (2) piloting of the NIH Single IRB Policy at our hub and (3) collaborating with the Streamlined, Multisite, Accelerated Resources for Trials (SMART) to implement SMART IRB authorization agreements. We are supporting the transformation of local hub infrastructure to promote efficiency. We adopted the Federal Demonstration Partnership Clinical Trials Subaward Agreement (FDP-CTA), the standard agreement system for network trial and study contracting. The collective impact of our participation in these national programs is transformative.
Our overall goal is to build on our infrastructure and to strengthen our collaborations with the TIN and the National Center for Data to Health (CD2H). Together with other CTSAs, we will continue to engage with new data sharing networks such as the National COVID Cohort Collaborative (N3C).
Services & Tools
Highlighted TIN services:
- Trial Innovation Network (TIN) Consults
The TIN Liaison can help you navigate services that may be available for your multisite clinical study.
Contact:
Jordan Daniel
jordandaniel@mednet.ucla.edu
- Community Engagement Studios
These consultative studios allow for diverse groups of stakeholders to be involved in the planning and implementation of research. Studios can facilitate guidance on identifying and addressing barriers to study participation as well as developing or refining recruitment materials and messages. Visit the TIN page for more information about their services.
Program Aims
Aim 1. Develop and optimize the infrastructure to provide continued support to TIN studies
- Promote awareness and active participation with the TIN.
- Leverage the regulatory infrastructure of the UCLA CTSI and the University of California Biomedical Research Acceleration, Integration and Development (UC BRAID), the consortium of five UC CTSAs.
- Utilize the CTSI’s integrated clinical research infrastructure to accelerate study activation.
- Develop innovative approaches to recruitment and retention.
Aim 2. Collaborate with NCATS’ National Data to Health Center (CD2H)
- Engage with CD2H to identify expertise and services, make resources FAIR (findable, accessible, interoperable, reusable) including implementation of Leaf and cross-linking of common data models.
- Work with CD2H to identify solutions to common informatics challenges and disseminate UCLA CTSI Hub developments.
Contact Us
For Network Capacity questions, please contact the below personnel.
Trial Innovation Network (TIN)
Primary Contact for TIN
Jordan Daniel
Administrator/Project Manager
jordandaniel@mednet.ucla.edu
Terra Hughes
TIN Liaison Team Member
Director, Office of Regulatory Affairs, CTSI
tnhughes@mednet.ucla.edu
Clinical Research Acceleration Unit (CRAU)
Hazel Xavier
(310) 794-8788
HXavier@mednet.ucla.edu
Recruitment Unit
Marianne Zachariah
Program Administrator
MZachariah@mednet.ucla.edu
Network Capacity Leadership
Network Capacity Investigators & Staff
