Boosting certain brain cells diminished hypersensitivity in Fragile X mice, study finds

CTSI/CART Pilot awardee, Dr. Carlos Portera-Cailliau, is the study's lead author

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Boosting the activity of inhibitory interneurons in Fragile X mice reduced their hypersensitivity to sensory stimuli, according to a new Neuron study led by UCLA Health researchers, and featuring collaborators from UC Davis and Lundbeck Biopharmaceuticals. 

Click here to read the full press release in the UCLA Health Newsroom.

CTSI supported this research through CTSI/CART Pilot funding awarded to Dr. Carlos Portera-Cailliau in 2019.

UCLA provides lots of internal grant support. For example, the Center for Autism Research and Treatment in partnership with CTSI provides small grants that encourage collaborations across labs on campus. This particular CART grant supported a collaboration between my lab and that of Michael Gandal (now at U. Penn) for the transcriptomic studies.

-Carlos Portera-Cailliau, PhD

Image source: Getty Images