Human Stem Cell & Genome Engineering Center (HSCGEC) (UCLA)

Supported by the Dr. Allen and Charlotte Ginsburg Center for Precision Genomic Medicine, UCLA’s Human Stem Cell & Genome Engineering Center (HSCGEC) provides end-to-end CRISPR genome-engineering, advanced pluripotent stem cell characterization and differentiation, and induced pluripotent stem cell (iPSC) reprogramming services. New CIRM-funded automation infrastructure ensures efficient, scalable, and high-quality research support.

Our services include:

Integration Free iPSC Reprogramming
• Human fibroblasts
• Peripheral blood mononuclear cells (PBMCs)

Pluripotent Stem Cell Characterization & Differentiation
• Whole Genome Sequencing–Based Genomic Stability Assay
• Immunocytochemistry for pluripotency markers (OCT4, SSEA4)
• Mycoplasma testing

CRISPR Genome Engineering
• Gene knockout
• Safe harbor locus engineering (e.g. AAVS1 site)
• Inducible Knockout/CRISPR activation/CRISPR inhibition
• Vector/gRNA design & cloning

Cell Line Banking
• Standardized QC & Authentication 
• Scalable Storage Solutions
• Fast & Reliable Retrieval

For more information, please visit the HSCGEC site.

Last updated
March 4, 2026