Scientists have re-created brain neurons of obese patients using "disease in a dish" technology, offering a new method to study the brain's role in obesity and possibly help tailor treatments to specific individuals.
"We have taken the first step in developing a great platform that potentially could be used to evaluate the effects of experimental therapeutics on specific patients," said Dhruv Sareen, PhD, assistant professor of Biomedical Sciences at Cedars-Sinai. "Ultimately, we are paving the way for personalized medicine, in which drugs could be customized for obese patients with different genetic backgrounds and disease statuses.”
Sareen is senior author of the CTSI-supported study about the findings, which was led by Cedars-Sinai investigators and published in the journal Cell Stem Cell.
Further reading:
The news release from Cedars-Sinai
The publication in Cell Stem Cell
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