Alcino Jose Silva

Title(s)Professor, Neurobiology
Professor, Psychiatry and Biobehavioral Sciences
SchoolMedicine
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Collapse Overview 
Collapse Overview
The long-term goal of our laboratory is to understand the molecular, cellular, circuit and behavioral mechanisms of how we know what we know (check out our researchmaps.org!).
Much of our work is focused on a crucial and exciting component of this question: memory. We are also leveraging our studies of memory and extraordinary cognition to develop treatments for cognitive disorders.

Collapse Research 
Collapse Research Activities and Funding
CCR5 Activation and Cognitive Dysfunction Caused by HIV-Proteins
NIH R01NS106969Sep 30, 2017 - May 31, 2022
Role: Principal Investigator
Molecular, Cellular and Circuit Mechnisms for Memory-linking deficits in Psychiatric Disorders
NIH R01MH113071Jun 1, 2017 - May 31, 2022
Role: Principal Investigator
Building and sharing next generation open-source, wireless, multichannel miniaturized microscopes for imaging activity in freely behaving mice
NIH U01NS094286Sep 30, 2015 - Jun 30, 2019
Role: Co-Principal Investigator
Forward Genetic Approaches to Mechanisms of Cortical Plasticity
NIH P50MH077972Apr 1, 2007 - Aug 31, 2012
Role: Principal Investigator
Molecular and Cellular Cognition Meeting
NIH R13MH073327Sep 22, 2004 - Jul 31, 2007
Role: Principal Investigator
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Collapse Bibliographic 
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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. A dual-pathway architecture for stress to disrupt agency and promote habit. Nature. 2025 Feb 19. Giovanniello JR, Paredes N, Wiener A, Ramírez-Armenta K, Oragwam C, Uwadia HO, Yu AL, Lim K, Pimenta JS, Vilchez GE, Nnamdi G, Wang A, Sehgal M, Reis FM, Sias AC, Silva AJ, Adhikari A, Malvaez M, Wassum KM. PMID: 39972126.
    View in: PubMed   Mentions:    Fields:    
  2. Compartmentalized dendritic plasticity in the mouse retrosplenial cortex links contextual memories formed close in time. Nat Neurosci. 2025 Feb 17. Sehgal M, Filho DA, Kastellakis G, Kim S, Lee J, Shen Y, Huang S, Lavi A, Fernandes G, Davila Mejia I, Martin SS, Pekcan A, Wu MS, Heo WD, Poirazi P, Trachtenberg JT, Silva AJ. PMID: 39962274.
    View in: PubMed   Mentions:    Fields:    
  3. Quantifying convergence and consistency. Eur J Neurosci. 2024 Nov; 60(10):6391-6394. Matiasz NJ, Wood J, Silva AJ. PMID: 39403790.
    View in: PubMed   Mentions: Translation:Humans
  4. A dual-pathway architecture enables chronic stress to disrupt agency and promote habit formation. bioRxiv. 2024 Sep 24. Giovanniello JR, Paredes N, Wiener A, Ramírez-Armenta K, Oragwam C, Uwadia HO, Yu AL, Lim K, Pimenta JS, Vilchez GE, Nnamdi G, Wang A, Sehgal M, Reis FM, Sias AC, Silva AJ, Adhikari A, Malvaez M, Wassum KM. PMID: 37873076; PMCID: PMC10592885.
    View in: PubMed   Mentions: 1  
  5. Intercellular Signaling Pathways as Therapeutic Targets for Vascular Dementia Repair. bioRxiv. 2024 Mar 27. Tian M, Kawaguchi R, Shen Y, Machnicki M, Villegas NG, Cooper DR, Montgomery N, Haring J, Lan R, Yuan AH, Williams CK, Magaki S, Vinters HV, Zhang Y, De Biase LM, Silva AJ, Carmichael ST. PMID: 38585718; PMCID: PMC10996514.
    View in: PubMed   Mentions:
  6. Control of feeding by a bottom-up midbrain-subthalamic pathway. Nat Commun. 2024 Mar 07; 15(1):2111. Reis FMCV, Maesta-Pereira S, Ollivier M, Schuette PJ, Sethi E, Miranda BA, Iniguez E, Chakerian M, Vaughn E, Sehgal M, Nguyen DCT, Yuan FTH, Torossian A, Ikebara JM, Kihara AH, Silva AJ, Kao JC, Khakh BS, Adhikari A. PMID: 38454000; PMCID: PMC10920831.
    View in: PubMed   Mentions:    Fields:    Translation:Animals
  7. Early Post-Natal Immune Activation Leads to Object Memory Deficits in Female Tsc2+/- Mice: The Importance of Including Both Sexes in Neuroscience Research. Biomedicines. 2024 Jan 17; 12(1). López-Aranda MF, Bach K, Bui R, Phan M, Lu O, Thadani C, Luchetti A, Mandanas R, Herrera I, López-Ávalos MD, Silva AJ. PMID: 38255309; PMCID: PMC10813674.
    View in: PubMed   Mentions:
  8. Behavioral and histological assessment of a novel treatment of neuroHIV in humanized mice. Res Sq. 2023 Dec 13. Levine AJ, Thadani C, Soontornniyomkij V, Lopez-Aranda MF, Mesa YG, Kitchen S, Rezek V, Silva A, Kolson DL. PMID: 38168407; PMCID: PMC10760308.
    View in: PubMed   Mentions:
  9. Aversive experience drives offline ensemble reactivation to link memories across days. bioRxiv. 2023 Aug 19. Zaki Y, Pennington ZT, Morales-Rodriguez D, Francisco TR, LaBanca AR, Dong Z, Lamsifer S, Segura SC, Chen HT, Wick ZC, Silva AJ, van der Meer M, Shuman T, Fenton A, Rajan K, Cai DJ. PMID: 36993254; PMCID: PMC10054942.
    View in: PubMed   Mentions:
  10. Miniscope-LFOV: A large-field-of-view, single-cell-resolution, miniature microscope for wired and wire-free imaging of neural dynamics in freely behaving animals. Sci Adv. 2023 04 21; 9(16):eadg3918. Guo C, Blair GJ, Sehgal M, Sangiuliano Jimka FN, Bellafard A, Silva AJ, Golshani P, Basso MA, Blair HT, Aharoni D. PMID: 37083539; PMCID: PMC10121160.
    View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
  11. Local memory allocation recruits memory ensembles across brain regions. Neuron. 2023 02 15; 111(4):470-480.e5. Lavi A, Sehgal M, de Sousa AF, Ter-Mkrtchyan D, Sisan F, Luchetti A, Okabe A, Bear C, Silva AJ. PMID: 36563678; PMCID: PMC10548338.
    View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
  12. A locus coeruleus-dorsal CA1 dopaminergic circuit modulates memory linking. Neuron. 2022 10 19; 110(20):3374-3388.e8. Chowdhury A, Luchetti A, Fernandes G, Filho DA, Kastellakis G, Tzilivaki A, Ramirez EM, Tran MY, Poirazi P, Silva AJ. PMID: 36041433; PMCID: PMC10508214.
    View in: PubMed   Mentions: 34     Fields:    Translation:Cells
  13. New research tools suggest a "levels-less" image of the behaving organism and dissolution of the reduction vs. anti-reduction dispute. Front Psychol. 2022; 13:990316. Bickle J, De Sousa AF, Silva AJ. PMID: 36110269; PMCID: PMC9470241.
    View in: PubMed   Mentions: 1  
  14. CCR5 closes the temporal window for memory linking. Nature. 2022 06; 606(7912):146-152. Shen Y, Zhou M, Cai D, Filho DA, Fernandes G, Cai Y, de Sousa AF, Tian M, Kim N, Lee J, Necula D, Zhou C, Li S, Salinas S, Liu A, Kang X, Kamata M, Lavi A, Huang S, Silva T, Heo WD, Silva AJ. PMID: 35614219; PMCID: PMC9197199.
    View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
  15. Role of Type I Interferon Signaling and Microglia in the Abnormal Long-term Potentiation and Object Place Recognition Deficits of Male Mice With a Mutation of the Tuberous Sclerosis 2 Gene. Biol Psychiatry Glob Open Sci. 2023 Jul; 3(3):451-459. López-Aranda MF, Boxx GM, Phan M, Bach K, Mandanas R, Herrera I, Taloma S, Thadani C, Lu O, Bui R, Liu S, Li N, Zhou Y, Cheng G, Silva AJ. PMID: 37519458; PMCID: PMC10382699.
    View in: PubMed   Mentions: 1  
  16. The emergence of molecular systems neuroscience. Mol Brain. 2022 01 04; 15(1):7. Shen Y, Luchetti A, Fernandes G, Do Heo W, Silva AJ. PMID: 34983613; PMCID: PMC8728933.
    View in: PubMed   Mentions: 5     Fields:    Translation:Cells
  17. Postnatal immune activation causes social deficits in a mouse model of tuberous sclerosis: Role of microglia and clinical implications. Sci Adv. 2021 Sep 17; 7(38):eabf2073. López-Aranda MF, Chattopadhyay I, Boxx GM, Fraley ER, Silva TK, Zhou M, Phan M, Herrera I, Taloma S, Mandanas R, Bach K, Gandal M, Geschwind DH, Cheng G, Rzhetsky A, White SA, Silva AJ. PMID: 34533985; PMCID: PMC8448451.
    View in: PubMed   Mentions: 9     Fields:    
  18. Dorsal premammillary projection to periaqueductal gray controls escape vigor from innate and conditioned threats. Elife. 2021 09 01; 10. Wang W, Schuette PJ, La-Vu MQ, Torossian A, Tobias BC, Ceko M, Kragel PA, Reis FM, Ji S, Sehgal M, Maesta-Pereira S, Chakerian M, Silva AJ, Canteras NS, Wager T, Kao JC, Adhikari A. PMID: 34468312; PMCID: PMC8457830.
    View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
  19. Dimensions and mechanisms of memory organization. Neuron. 2021 09 01; 109(17):2649-2662. de Sousa AF, Chowdhury A, Silva AJ. PMID: 34242564; PMCID: PMC8416710.
    View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
  20. Experiment Selection in Meta-Analytic Piecemeal Causal Discovery. IEEE Access. 2021; 9:97929-97941. Matiasz NJ, Wood J, Wang W, Silva AJ, Hsu W. PMID: 34532201; PMCID: PMC8442252.
    View in: PubMed   Mentions: 1  
  21. Chemokine Receptors CC Chemokine Receptor 5 and C-X-C Motif Chemokine Receptor 4 Are New Therapeutic Targets for Brain Recovery after Traumatic Brain Injury. J Neurotrauma. 2021 07 15; 38(14):2003-2017. Liraz-Zaltsman S, Friedman-Levi Y, Shabashov-Stone D, Gincberg G, Atrakcy-Baranes D, Joy MT, Carmichael ST, Silva AJ, Shohami E. PMID: 33256497.
    View in: PubMed   Mentions: 13     Fields:    Translation:Animals
  22. Pharmacological blockers of CCR5 and CXCR4 improve recovery after traumatic brain injury. Exp Neurol. 2021 04; 338:113604. Friedman-Levi Y, Liraz-Zaltsman S, Shemesh C, Rosenblatt K, Kesner EL, Gincberg G, Carmichael ST, Silva AJ, Shohami E. PMID: 33453212.
    View in: PubMed   Mentions: 13     Fields:    Translation:Animals
  23. Breakdown of spatial coding and interneuron synchronization in epileptic mice. Nat Neurosci. 2020 02; 23(2):229-238. Shuman T, Aharoni D, Cai DJ, Lee CR, Chavlis S, Page-Harley L, Vetere LM, Feng Y, Yang CY, Mollinedo-Gajate I, Chen L, Pennington ZT, Taxidis J, Flores SE, Cheng K, Javaherian M, Kaba CC, Rao N, La-Vu M, Pandi I, Shtrahman M, Bakhurin KI, Masmanidis SC, Khakh BS, Poirazi P, Silva AJ, Golshani P. PMID: 31907437; PMCID: PMC7259114.
    View in: PubMed   Mentions: 88     Fields:    Translation:AnimalsCells
  24. Human Memories Can Be Linked by Temporal Proximity. Front Hum Neurosci. 2019; 13:315. Yetton BD, Cai DJ, Spoormaker VI, Silva AJ, Mednick SC. PMID: 31572150; PMCID: PMC6753892.
    View in: PubMed   Mentions: 11  
  25. Getting the full picture. Elife. 2019 03 26; 8. Luchetti A, Chowdhury A, Silva AJ. PMID: 30912744; PMCID: PMC6435316.
    View in: PubMed   Mentions:    Fields:    
  26. Excitatory neuron-specific SHP2-ERK signaling network regulates synaptic plasticity and memory. Sci Signal. 2019 03 05; 12(571). Ryu HH, Kim T, Kim JW, Kang M, Park P, Kim YG, Kim H, Ha J, Choi JE, Lee J, Lim CS, Kim CH, Kim SJ, Silva AJ, Kaang BK, Lee YS. PMID: 30837304; PMCID: PMC6800025.
    View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
  27. CCR5 Is a Therapeutic Target for Recovery after Stroke and Traumatic Brain Injury. Cell. 2019 02 21; 176(5):1143-1157.e13. Joy MT, Ben Assayag E, Shabashov-Stone D, Liraz-Zaltsman S, Mazzitelli J, Arenas M, Abduljawad N, Kliper E, Korczyn AD, Thareja NS, Kesner EL, Zhou M, Huang S, Silva TK, Katz N, Bornstein NM, Silva AJ, Shohami E, Carmichael ST. PMID: 30794775; PMCID: PMC7259116.
    View in: PubMed   Mentions: 161     Fields:    Translation:HumansAnimalsCells
  28. All the light that we can see: a new era in miniaturized microscopy. Nat Methods. 2019 Jan; 16(1):11-13. Aharoni D, Khakh BS, Silva AJ, Golshani P. PMID: 30573833; PMCID: PMC8320687.
    View in: PubMed   Mentions: 66     Fields:    Translation:Animals
  29. The mouse as a model for neuropsychiatric drug development. Curr Biol. 2018 09 10; 28(17):R909-R914. Howe JR, Bear MF, Golshani P, Klann E, Lipton SA, Mucke L, Sahin M, Silva AJ. PMID: 30205056; PMCID: PMC8163022.
    View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
  30. ResearchMaps.org for integrating and planning research. PLoS One. 2018; 13(5):e0195271. Matiasz NJ, Wood J, Doshi P, Speier W, Beckemeyer B, Wang W, Hsu W, Silva AJ. PMID: 29723213; PMCID: PMC5933701.
    View in: PubMed   Mentions: 2     Fields:    
  31. Enhancement of Brain d-Serine Mediates Recovery of Cognitive Function after Traumatic Brain Injury. J Neurotrauma. 2018 07 15; 35(14):1667-1680. Liraz-Zaltsman S, Slusher B, Atrakchi-Baranes D, Rosenblatt K, Friedman Levi Y, Kesner E, Silva AJ, Biegon A, Shohami E. PMID: 29648983.
    View in: PubMed   Mentions: 6     Fields:    Translation:Animals
  32. Brain-wide Electrical Spatiotemporal Dynamics Encode Depression Vulnerability. Cell. 2018 03 22; 173(1):166-180.e14. Hultman R, Ulrich K, Sachs BD, Blount C, Carlson DE, Ndubuizu N, Bagot RC, Parise EM, Vu MT, Gallagher NM, Wang J, Silva AJ, Deisseroth K, Mague SD, Caron MG, Nestler EJ, Carin L, Dzirasa K. PMID: 29502969; PMCID: PMC6005365.
    View in: PubMed   Mentions: 83     Fields:    Translation:Animals
  33. Randomised controlled trial of simvastatin treatment for autism in young children with neurofibromatosis type 1 (SANTA). Mol Autism. 2018; 9:12. Stivaros S, Garg S, Tziraki M, Cai Y, Thomas O, Mellor J, Morris AA, Jim C, Szumanska-Ryt K, Parkes LM, Haroon HA, Montaldi D, Webb N, Keane J, Castellanos FX, Silva AJ, Huson S, Williams S, Gareth Evans D, Emsley R, Green J, SANTA Consortium. PMID: 29484149; PMCID: PMC5824534.
    View in: PubMed   Mentions: 35     Fields:    Translation:Humans
  34. Memory formation depends on both synapse-specific modifications of synaptic strength and cell-specific increases in excitability. Nat Neurosci. 2018 03; 21(3):309-314. Lisman J, Cooper K, Sehgal M, Silva AJ. PMID: 29434376; PMCID: PMC5915620.
    View in: PubMed   Mentions: 142     Fields:    Translation:HumansAnimalsCells
  35. Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory. Nat Commun. 2018 01 29; 9(1):422. Frank AC, Huang S, Zhou M, Gdalyahu A, Kastellakis G, Silva TK, Lu E, Wen X, Poirazi P, Trachtenberg JT, Silva AJ. PMID: 29379017; PMCID: PMC5789055.
    View in: PubMed   Mentions: 78     Fields:    Translation:AnimalsCells
  36. Testing the excitation/inhibition imbalance hypothesis in a mouse model of the autism spectrum disorder: in vivo neurospectroscopy and molecular evidence for regional phenotypes. Mol Autism. 2017; 8:47. Gonçalves J, Violante IR, Sereno J, Leitão RA, Cai Y, Abrunhosa A, Silva AP, Silva AJ, Castelo-Branco M. PMID: 28932379; PMCID: PMC5605987.
    View in: PubMed   Mentions: 41     Fields:    Translation:Animals
  37. Miniaturized two-photon microscope: seeing clearer and deeper into the brain. Light Sci Appl. 2017 Aug; 6(8):e17104. Silva AJ. PMID: 30167288; PMCID: PMC6062320.
    View in: PubMed   Mentions: 15  
  38. Spatial working memory in neurofibromatosis 1: Altered neural activity and functional connectivity. Neuroimage Clin. 2017; 15:801-811. Ibrahim AFA, Montojo CA, Haut KM, Karlsgodt KH, Hansen L, Congdon E, Rosser T, Bilder RM, Silva AJ, Bearden CE. PMID: 28725547; PMCID: PMC5501884.
    View in: PubMed   Mentions: 14     Fields:    Translation:Humans
  39. Memory's Intricate Web. Sci Am. 2017 Jun 20; 317(1):30-37. Silva AJ. PMID: 28632232; PMCID: PMC5915626.
    View in: PubMed   Mentions: 4     Fields:    
  40. Noonan syndrome-associated SHP2 mutation differentially modulates the expression of postsynaptic receptors according to developmental maturation. Neurosci Lett. 2017 05 10; 649:41-47. Oh JY, Rhee S, Silva AJ, Lee YS, Kim HK. PMID: 28366775; PMCID: PMC6844293.
    View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
  41. Risky Decision Making in Neurofibromatosis Type 1: An Exploratory Study. Biol Psychiatry Cogn Neurosci Neuroimaging. 2017 Mar; 2(2):170-179. Jonas RK, Roh E, Montojo CA, Pacheco LA, Rosser T, Silva AJ, Bearden CE. PMID: 28736755; PMCID: PMC5518467.
    View in: PubMed   Mentions: 2     Fields:    
  42. Computer-Aided Experiment Planning toward Causal Discovery in Neuroscience. Front Neuroinform. 2017; 11:12. Matiasz NJ, Wood J, Wang W, Silva AJ, Hsu W. PMID: 28243197; PMCID: PMC5304468.
    View in: PubMed   Mentions: 3  
  43. CCR5 is a suppressor for cortical plasticity and hippocampal learning and memory. Elife. 2016 12 20; 5. Zhou M, Greenhill S, Huang S, Silva TK, Sano Y, Wu S, Cai Y, Nagaoka Y, Sehgal M, Cai DJ, Lee YS, Fox K, Silva AJ. PMID: 27996938; PMCID: PMC5213777.
    View in: PubMed   Mentions: 67     Fields:    Translation:AnimalsCells
  44. Randomized placebo-controlled study of lovastatin in children with neurofibromatosis type 1. Neurology. 2016 Dec 13; 87(24):2575-2584. Payne JM, Barton B, Ullrich NJ, Cantor A, Hearps SJ, Cutter G, Rosser T, Walsh KS, Gioia GA, Wolters PL, Tonsgard J, Schorry E, Viskochil D, Klesse L, Fisher M, Gutmann DH, Silva AJ, Hunter SJ, Rey-Casserly C, Cantor NL, Byars AW, Stavinoha PL, Ackerson JD, Armstrong CL, Isenberg J, O'Neil SH, Packer RJ, Korf B, Acosta MT, North KN, NF Clinical Trials Consortium. PMID: 27956565; PMCID: PMC5207004.
    View in: PubMed   Mentions: 42     Fields:    Translation:Humans
  45. Linking Memories across Time via Neuronal and Dendritic Overlaps in Model Neurons with Active Dendrites. Cell Rep. 2016 11 01; 17(6):1491-1504. Kastellakis G, Silva AJ, Poirazi P. PMID: 27806290; PMCID: PMC5149530.
    View in: PubMed   Mentions: 43     Fields:    Translation:Cells
  46. Corrigendum: The need for novel informatics tools for integrating and planning research in molecular and cellular cognition. Learn Mem. 2016 11; 23(11):668. Silva AJ, Müller KR. PMID: 27918288; PMCID: PMC5066599.
    View in: PubMed   Mentions:    Fields:    
  47. Molecular and Cellular Mechanisms for Trapping and Activating Emotional Memories. PLoS One. 2016; 11(8):e0161655. Rogerson T, Jayaprakash B, Cai DJ, Sano Y, Lee YS, Zhou Y, Bekal P, Deisseroth K, Silva AJ. PMID: 27579481; PMCID: PMC5007047.
    View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
  48. A shared neural ensemble links distinct contextual memories encoded close in time. Nature. 2016 06 02; 534(7605):115-8. Cai DJ, Aharoni D, Shuman T, Shobe J, Biane J, Song W, Wei B, Veshkini M, La-Vu M, Lou J, Flores SE, Kim I, Sano Y, Zhou M, Baumgaertel K, Lavi A, Kamata M, Tuszynski M, Mayford M, Golshani P, Silva AJ. PMID: 27251287; PMCID: PMC5063500.
    View in: PubMed   Mentions: 421     Fields:    Translation:AnimalsCells
  49. Advances and Future Directions for Tuberous Sclerosis Complex Research: Recommendations From the 2015 Strategic Planning Conference. Pediatr Neurol. 2016 07; 60:1-12. Sahin M, Henske EP, Manning BD, Ess KC, Bissler JJ, Klann E, Kwiatkowski DJ, Roberds SL, Silva AJ, Hillaire-Clarke CS, Young LR, Zervas M, Mamounas LA, Tuberous Sclerosis Complex Working Group to Update the Research Plan. PMID: 27267556; PMCID: PMC4921275.
    View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimals
  50. Hijacking translation in addiction. Elife. 2016 Mar 01; 5. Izquierdo A, Silva AJ. PMID: 26929992; PMCID: PMC4786444.
    View in: PubMed   Mentions:    Fields:    Translation:Humans
  51. A randomized placebo-controlled lovastatin trial for neurobehavioral function in neurofibromatosis I. Ann Clin Transl Neurol. 2016 04; 3(4):266-79. Bearden CE, Hellemann GS, Rosser T, Montojo C, Jonas R, Enrique N, Pacheco L, Hussain SA, Wu JY, Ho JS, McGough JJ, Sugar CA, Silva AJ. PMID: 27081657; PMCID: PMC4818747.
    View in: PubMed   Mentions: 29     Fields:    
  52. Resting state functional MRI reveals abnormal network connectivity in neurofibromatosis 1. Hum Brain Mapp. 2015 Nov; 36(11):4566-81. Tomson SN, Schreiner MJ, Narayan M, Rosser T, Enrique N, Silva AJ, Allen GI, Bookheimer SY, Bearden CE. PMID: 26304096; PMCID: PMC4619152.
    View in: PubMed   Mentions: 22     Fields:    Translation:Humans
  53. The need for novel informatics tools for integrating and planning research in molecular and cellular cognition. Learn Mem. 2015 Sep; 22(9):494-8. Silva AJ, Müller KR. PMID: 26286658; PMCID: PMC4561409.
    View in: PubMed   Mentions: 4     Fields:    Translation:Animals
  54. The third international meeting on genetic disorders in the RAS/MAPK pathway: towards a therapeutic approach. Am J Med Genet A. 2015 Aug; 167A(8):1741-6. Korf B, Ahmadian R, Allanson J, Aoki Y, Bakker A, Wright EB, Denger B, Elgersma Y, Gelb BD, Gripp KW, Kerr B, Kontaridis M, Lazaro C, Linardic C, Lozano R, MacRae CA, Messiaen L, Mulero-Navarro S, Neel B, Plotkin S, Rauen KA, Roberts A, Silva AJ, Sittampalam SG, Zhang C, Schoyer L. PMID: 25900621; PMCID: PMC4515140.
    View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
  55. Synaptic clustering within dendrites: an emerging theory of memory formation. Prog Neurobiol. 2015 Mar; 126:19-35. Kastellakis G, Cai DJ, Mednick SC, Silva AJ, Poirazi P. PMID: 25576663; PMCID: PMC4361279.
    View in: PubMed   Mentions: 81     Fields:    Translation:HumansAnimalsCells
  56. CREB regulates memory allocation in the insular cortex. Curr Biol. 2014 Dec 01; 24(23):2833-7. Sano Y, Shobe JL, Zhou M, Huang S, Shuman T, Cai DJ, Golshani P, Kamata M, Silva AJ. PMID: 25454591; PMCID: PMC4743759.
    View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
  57. Mechanism and treatment for learning and memory deficits in mouse models of Noonan syndrome. Nat Neurosci. 2014 Dec; 17(12):1736-43. Lee YS, Ehninger D, Zhou M, Oh JY, Kang M, Kwak C, Ryu HH, Butz D, Araki T, Cai Y, Balaji J, Sano Y, Nam CI, Kim HK, Kaang BK, Burger C, Neel BG, Silva AJ. PMID: 25383899; PMCID: PMC4716736.
    View in: PubMed   Mentions: 86     Fields:    Translation:HumansAnimals
  58. Maternal inflammation contributes to brain overgrowth and autism-associated behaviors through altered redox signaling in stem and progenitor cells. Stem Cell Reports. 2014 Nov 11; 3(5):725-34. Le Belle JE, Sperry J, Ngo A, Ghochani Y, Laks DR, López-Aranda M, Silva AJ, Kornblum HI. PMID: 25418720; PMCID: PMC4235743.
    View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
  59. Temporal and region-specific requirements of αCaMKII in spatial and contextual learning. J Neurosci. 2014 Aug 20; 34(34):11180-7. Achterberg KG, Buitendijk GH, Kool MJ, Goorden SM, Post L, Slump DE, Silva AJ, van Woerden GM, Kushner SA, Elgersma Y. PMID: 25143599; PMCID: PMC4340969.
    View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
  60. Encoding and storage of spatial information in the retrosplenial cortex. Proc Natl Acad Sci U S A. 2014 Jun 10; 111(23):8661-6. Czajkowski R, Jayaprakash B, Wiltgen B, Rogerson T, Guzman-Karlsson MC, Barth AL, Trachtenberg JT, Silva AJ. PMID: 24912150; PMCID: PMC4060653.
    View in: PubMed   Mentions: 95     Fields:    Translation:AnimalsCells
  61. Synaptic tagging during memory allocation. Nat Rev Neurosci. 2014 Mar; 15(3):157-69. Rogerson T, Cai DJ, Frank A, Sano Y, Shobe J, Lopez-Aranda MF, Silva AJ. PMID: 24496410; PMCID: PMC3992944.
    View in: PubMed   Mentions: 130     Fields:    Translation:HumansAnimalsCells
  62. The need for research maps to navigate published work and inform experiment planning. Neuron. 2013 Aug 07; 79(3):411-5. Landreth A, Silva AJ. PMID: 23931992.
    View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
  63. mTOR regulates tau phosphorylation and degradation: implications for Alzheimer's disease and other tauopathies. Aging Cell. 2013 Jun; 12(3):370-80. Caccamo A, Magrì A, Medina DX, Wisely EV, López-Aranda MF, Silva AJ, Oddo S. PMID: 23425014; PMCID: PMC3655115.
    View in: PubMed   Mentions: 174     Fields:    Translation:HumansAnimalsCells
  64. Forebrain engraftment by human glial progenitor cells enhances synaptic plasticity and learning in adult mice. Cell Stem Cell. 2013 Mar 07; 12(3):342-53. Han X, Chen M, Wang F, Windrem M, Wang S, Shanz S, Xu Q, Oberheim NA, Bekar L, Betstadt S, Silva AJ, Takano T, Goldman SA, Nedergaard M. PMID: 23472873; PMCID: PMC3700554.
    View in: PubMed   Mentions: 288     Fields:    Translation:HumansAnimalsCells
  65. mTOR Inhibition ameliorates cognitive and affective deficits caused by Disc1 knockdown in adult-born dentate granule neurons. Neuron. 2013 Feb 20; 77(4):647-54. Zhou M, Li W, Huang S, Song J, Kim JY, Tian X, Kang E, Sano Y, Liu C, Balaji J, Wu S, Zhou Y, Zhou Y, Parivash SN, Ehninger D, He L, Song H, Ming GL, Silva AJ. PMID: 23439118; PMCID: PMC3586374.
    View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
  66. Alterations in white matter microstructure in neurofibromatosis-1. PLoS One. 2012; 7(10):e47854. Karlsgodt KH, Rosser T, Lutkenhoff ES, Cannon TD, Silva A, Bearden CE. PMID: 23094098; PMCID: PMC3477133.
    View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
  67. Neurofibromatosis type 1: modeling CNS dysfunction. J Neurosci. 2012 Oct 10; 32(41):14087-93. Gutmann DH, Parada LF, Silva AJ, Ratner N. PMID: 23055477; PMCID: PMC3477849.
    View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
  68. The Learning Disabilities Network (LeaDNet): using neurofibromatosis type 1 (NF1) as a paradigm for translational research. Am J Med Genet A. 2012 Sep; 158A(9):2225-32. Acosta MT, Bearden CE, Castellanos FX, Castellanos XF, Cutting L, Elgersma Y, Gioia G, Gutmann DH, Lee YS, Legius E, Muenke M, North K, Parada LF, Ratner N, Hunter-Schaedle K, Silva AJ. PMID: 22821737; PMCID: PMC4074877.
    View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
  69. Associative fear learning enhances sparse network coding in primary sensory cortex. Neuron. 2012 Jul 12; 75(1):121-32. Gdalyahu A, Tring E, Polack PO, Gruver R, Golshani P, Fanselow MS, Silva AJ, Trachtenberg JT. PMID: 22794266; PMCID: PMC3398404.
    View in: PubMed   Mentions: 46     Fields:    Translation:Animals
  70. α-Calcium calmodulin kinase II modulates the temporal structure of hippocampal bursting patterns. PLoS One. 2012; 7(2):e31649. Cho J, Bhatt R, Elgersma Y, Silva AJ. PMID: 22363696; PMCID: PMC3282754.
    View in: PubMed   Mentions: 5     Fields:    Translation:Animals
  71. CaMKII binding to GluN2B is critical during memory consolidation. EMBO J. 2012 Mar 07; 31(5):1203-16. Halt AR, Dallapiazza RF, Zhou Y, Stein IS, Qian H, Juntti S, Wojcik S, Brose N, Silva AJ, Hell JW. PMID: 22234183; PMCID: PMC3297991.
    View in: PubMed   Mentions: 139     Fields:    Translation:AnimalsCells
  72. Obituary: A career that transformed neuroscience. Brain Res Bull. 2011 Nov 25; 86(5-6):285-6. Silva AJ. PMID: 21930192.
    View in: PubMed   Mentions:    Fields:    
  73. NMDA mediated contextual conditioning changes miRNA expression. PLoS One. 2011; 6(9):e24682. Kye MJ, Neveu P, Lee YS, Zhou M, Steen JA, Sahin M, Kosik KS, Silva AJ. PMID: 21931811; PMCID: PMC3171446.
    View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
  74. Modeling hyperactivity: of mice and men. Nat Med. 2011 May; 17(5):541-2. Lee YS, Silva AJ. PMID: 21546967.
    View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
  75. Rapamycin for treating Tuberous sclerosis and Autism spectrum disorders. Trends Mol Med. 2011 Feb; 17(2):78-87. Ehninger D, Silva AJ. PMID: 21115397; PMCID: PMC3075964.
    View in: PubMed   Mentions: 97     Fields:    Translation:HumansAnimalsCells
  76. Constitutively active H-ras accelerates multiple forms of plasticity in developing visual cortex. Proc Natl Acad Sci U S A. 2010 Nov 02; 107(44):19026-31. Kaneko M, Cheetham CE, Lee YS, Silva AJ, Stryker MP, Fox K. PMID: 20937865; PMCID: PMC2973899.
    View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
  77. Increased levels of anxiety-related behaviors in a Tsc2 dominant negative transgenic mouse model of tuberous sclerosis. Behav Genet. 2011 May; 41(3):357-63. Ehninger D, Silva AJ. PMID: 20882401; PMCID: PMC3102774.
    View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
  78. The hippocampus plays a selective role in the retrieval of detailed contextual memories. Curr Biol. 2010 Aug 10; 20(15):1336-44. Wiltgen BJ, Zhou M, Cai Y, Balaji J, Karlsson MG, Parivash SN, Li W, Silva AJ. PMID: 20637623; PMCID: PMC2928141.
    View in: PubMed   Mentions: 118     Fields:    Translation:Animals
  79. Neurofibromin regulates corticostriatal inhibitory networks during working memory performance. Proc Natl Acad Sci U S A. 2010 Jul 20; 107(29):13141-6. Shilyansky C, Karlsgodt KH, Cummings DM, Sidiropoulou K, Hardt M, James AS, Ehninger D, Bearden CE, Poirazi P, Jentsch JD, Cannon TD, Levine MS, Silva AJ. PMID: 20624961; PMCID: PMC2919968.
    View in: PubMed   Mentions: 84     Fields:    Translation:HumansAnimalsCells
  80. CaMKII "autonomy" is required for initiating but not for maintaining neuronal long-term information storage. J Neurosci. 2010 Jun 16; 30(24):8214-20. Buard I, Coultrap SJ, Freund RK, Lee YS, Dell'Acqua ML, Silva AJ, Bayer KU. PMID: 20554872; PMCID: PMC2891520.
    View in: PubMed   Mentions: 87     Fields:    Translation:AnimalsCells
  81. Muscleblind1, but not Dmpk or Six5, contributes to a complex phenotype of muscular and motivational deficits in mouse models of myotonic dystrophy. PLoS One. 2010 Mar 25; 5(3):e9857. Matynia A, Ng CH, Dansithong W, Chiang A, Silva AJ, Reddy S. PMID: 20360842; PMCID: PMC2845609.
    View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimals
  82. Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nat Neurosci. 2010 Apr; 13(4):423-30. Feng J, Zhou Y, Campbell SL, Le T, Li E, Sweatt JD, Silva AJ, Fan G. PMID: 20228804; PMCID: PMC3060772.
    View in: PubMed   Mentions: 495     Fields:    Translation:AnimalsCells
  83. Proceedings from the 2009 genetic syndromes of the Ras/MAPK pathway: From bedside to bench and back. Am J Med Genet A. 2010 Jan; 152A(1):4-24. Rauen KA, Schoyer L, McCormick F, Lin AE, Allanson JE, Stevenson DA, Gripp KW, Neri G, Carey JC, Legius E, Tartaglia M, Schubbert S, Roberts AE, Gelb BD, Shannon K, Gutmann DH, McMahon M, Guerra C, Fagin JA, Yu B, Aoki Y, Neel BG, Balmain A, Drake RR, Nolan GP, Zenker M, Bollag G, Sebolt-Leopold J, Gibbs JB, Silva AJ, Patton EE, Viskochil DH, Kieran MW, Korf BR, Hagerman RJ, Packer RJ, Melese T. PMID: 20014119; PMCID: PMC4051786.
    View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
  84. Molecular and cellular approaches to memory allocation in neural circuits. Science. 2009 Oct 16; 326(5951):391-5. Silva AJ, Zhou Y, Rogerson T, Shobe J, Balaji J. PMID: 19833959; PMCID: PMC2844777.
    View in: PubMed   Mentions: 125     Fields:    Translation:AnimalsCells
  85. CREB regulates excitability and the allocation of memory to subsets of neurons in the amygdala. Nat Neurosci. 2009 Nov; 12(11):1438-43. Zhou Y, Won J, Karlsson MG, Zhou M, Rogerson T, Balaji J, Neve R, Poirazi P, Silva AJ. PMID: 19783993; PMCID: PMC2783698.
    View in: PubMed   Mentions: 260     Fields:    Translation:AnimalsCells
  86. Genetics and neuropsychiatric disorders: treatment during adulthood. Nat Med. 2009 Aug; 15(8):849-50. Ehninger D, Silva AJ. PMID: 19661989.
    View in: PubMed   Mentions: 14     Fields:    Translation:Humans
  87. Dissociated fear and spatial learning in mice with deficiency of ataxin-2. PLoS One. 2009 Jul 20; 4(7):e6235. Huynh DP, Maalouf M, Silva AJ, Schweizer FE, Pulst SM. PMID: 19617910; PMCID: PMC2707006.
    View in: PubMed   Mentions: 23     Fields:    Translation:Animals
  88. Adult reversal of cognitive phenotypes in neurodevelopmental disorders. J Neurodev Disord. 2009 Jun; 1(2):150-7. Silva AJ, Ehninger D. PMID: 19812701; PMCID: PMC2755132.
    View in: PubMed   Mentions: 17     Fields:    
  89. DNA hypomethylation restricted to the murine forebrain induces cortical degeneration and impairs postnatal neuronal maturation. Hum Mol Genet. 2009 Aug 01; 18(15):2875-88. Hutnick LK, Golshani P, Namihira M, Xue Z, Matynia A, Yang XW, Silva AJ, Schweizer FE, Fan G. PMID: 19433415; PMCID: PMC2706688.
    View in: PubMed   Mentions: 95     Fields:    Translation:AnimalsCells
  90. The molecular and cellular biology of enhanced cognition. Nat Rev Neurosci. 2009 Feb; 10(2):126-40. Lee YS, Silva AJ. PMID: 19153576; PMCID: PMC2664745.
    View in: PubMed   Mentions: 172     Fields:    Translation:HumansAnimalsCells
  91. Reversing neurodevelopmental disorders in adults. Neuron. 2008 Dec 26; 60(6):950-60. Ehninger D, Li W, Fox K, Stryker MP, Silva AJ. PMID: 19109903; PMCID: PMC2710296.
    View in: PubMed   Mentions: 92     Fields:    Translation:HumansAnimals
  92. Neurofibromin regulation of ERK signaling modulates GABA release and learning. Cell. 2008 Oct 31; 135(3):549-60. Cui Y, Costa RM, Murphy GG, Elgersma Y, Zhu Y, Gutmann DH, Parada LF, Mody I, Silva AJ. PMID: 18984165; PMCID: PMC2673196.
    View in: PubMed   Mentions: 246     Fields:    Translation:AnimalsCells
  93. Autophosphorylation of alphaCaMKII is differentially involved in new learning and unlearning mechanisms of memory extinction. Learn Mem. 2008 Nov; 15(11):837-43. Kimura R, Silva AJ, Ohno M. PMID: 18984565; PMCID: PMC2632808.
    View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
  94. Calmodulin-kinases: modulators of neuronal development and plasticity. Neuron. 2008 Sep 25; 59(6):914-31. Wayman GA, Lee YS, Tokumitsu H, Silva AJ, Silva A, Soderling TR. PMID: 18817731; PMCID: PMC2664743.
    View in: PubMed   Mentions: 273     Fields:    Translation:HumansAnimalsCells
  95. Effect of simvastatin on cognitive functioning in children with neurofibromatosis type 1: a randomized controlled trial. JAMA. 2008 Jul 16; 300(3):287-94. Krab LC, de Goede-Bolder A, Aarsen FK, Pluijm SM, Bouman MJ, van der Geest JN, Lequin M, Catsman CE, Arts WF, Kushner SA, Silva AJ, de Zeeuw CI, Moll HA, Elgersma Y. PMID: 18632543; PMCID: PMC2664742.
    View in: PubMed   Mentions: 88     Fields:    Translation:Humans
  96. Reversal of learning deficits in a Tsc2+/- mouse model of tuberous sclerosis. Nat Med. 2008 Aug; 14(8):843-8. Ehninger D, Han S, Shilyansky C, Zhou Y, Li W, Kwiatkowski DJ, Ramesh V, Silva AJ. PMID: 18568033; PMCID: PMC2664098.
    View in: PubMed   Mentions: 417     Fields:    Translation:AnimalsCells
  97. A high through-put reverse genetic screen identifies two genes involved in remote memory in mice. PLoS One. 2008 May 07; 3(5):e2121. Matynia A, Anagnostaras SG, Wiltgen BJ, Lacuesta M, Fanselow MS, Silva AJ. PMID: 18464936; PMCID: PMC2373872.
    View in: PubMed   Mentions: 16     Fields:    Translation:Animals
  98. Molecular aspects, clinical aspects and possible treatment modalities for Costello syndrome: Proceedings from the 1st International Costello Syndrome Research Symposium 2007. Am J Med Genet A. 2008 May 01; 146A(9):1205-17. Rauen KA, Hefner E, Carrillo K, Taylor J, Messier L, Aoki Y, Gripp KW, Matsubara Y, Proud VK, Hammond P, Allanson JE, Delrue MA, Axelrad ME, Lin AE, Doyle DA, Kerr B, Carey JC, McCormick F, Silva AJ, Kieran MW, Hinek A, Nguyen TT, Schoyer L. PMID: 18412122.
    View in: PubMed   Mentions: 6     Fields:    Translation:Humans
  99. The science of research: the principles underlying the discovery of cognitive and other biological mechanisms. J Physiol Paris. 2007 Jul-Nov; 101(4-6):203-13. Silva AJ. PMID: 18280120.
    View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
  100. Interactions between the NR2B receptor and CaMKII modulate synaptic plasticity and spatial learning. J Neurosci. 2007 Dec 12; 27(50):13843-53. Zhou Y, Takahashi E, Li W, Halt A, Wiltgen B, Ehninger D, Li GD, Hell JW, Kennedy MB, Silva AJ. PMID: 18077696; PMCID: PMC6673634.
    View in: PubMed   Mentions: 91     Fields:    Translation:AnimalsCells
  101. Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice. Proc Natl Acad Sci U S A. 2007 Nov 13; 104(46):18280-5. Li W, Zhou Y, Jentsch JD, Brown RA, Tian X, Ehninger D, Hennah W, Peltonen L, Lönnqvist J, Huttunen MO, Kaprio J, Trachtenberg JT, Silva AJ, Cannon TD. PMID: 17984054; PMCID: PMC2084334.
    View in: PubMed   Mentions: 101     Fields:    Translation:Animals
  102. Molecular and cellular mechanisms of memory allocation in neuronetworks. Neurobiol Learn Mem. 2008 Mar; 89(3):285-92. Won J, Silva AJ. PMID: 17962049; PMCID: PMC2673809.
    View in: PubMed   Mentions: 31     Fields:    Translation:Humans
  103. Kinase activity is not required for alphaCaMKII-dependent presynaptic plasticity at CA3-CA1 synapses. Nat Neurosci. 2007 Sep; 10(9):1125-7. Hojjati MR, van Woerden GM, Tyler WJ, Giese KP, Silva AJ, Pozzo-Miller L, Elgersma Y. PMID: 17660813; PMCID: PMC2804046.
    View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
  104. Neuronal competition and selection during memory formation. Science. 2007 Apr 20; 316(5823):457-60. Han JH, Kushner SA, Yiu AP, Cole CJ, Matynia A, Brown RA, Neve RL, Guzowski JF, Silva AJ, Josselyn SA. PMID: 17446403.
    View in: PubMed   Mentions: 312     Fields:    Translation:AnimalsCells
  105. Memory for context becomes less specific with time. Learn Mem. 2007 Apr; 14(4):313-7. Wiltgen BJ, Silva AJ. PMID: 17522020.
    View in: PubMed   Mentions: 132     Fields:    Translation:Animals
  106. Investigation of age-related cognitive decline using mice as a model system: neurophysiological correlates. Am J Geriatr Psychiatry. 2006 Dec; 14(12):1012-21. Murphy GG, Shah V, Hell JW, Silva AJ. PMID: 17138808.
    View in: PubMed   Mentions: 18     Fields:    Translation:Animals
  107. Investigation of age-related cognitive decline using mice as a model system: behavioral correlates. Am J Geriatr Psychiatry. 2006 Dec; 14(12):1004-11. Murphy GG, Rahnama NP, Silva AJ. PMID: 17138807.
    View in: PubMed   Mentions: 22     Fields:    Translation:Animals
  108. Stability of recent and remote contextual fear memory. Learn Mem. 2006 Jul-Aug; 13(4):451-7. Frankland PW, Ding HK, Takahashi E, Suzuki A, Kida S, Silva AJ. PMID: 16882861; PMCID: PMC1538922.
    View in: PubMed   Mentions: 104     Fields:    Translation:Animals
  109. Differential effects of alphaCaMKII mutation on hippocampal learning and changes in intrinsic neuronal excitability. Eur J Neurosci. 2006 Apr; 23(8):2235-40. Ohno M, Sametsky EA, Silva AJ, Disterhoft JF. PMID: 16630070.
    View in: PubMed   Mentions: 20  Translation:AnimalsCells
  110. Neurofibromatosis type 1: new insights into neurocognitive issues. Curr Neurol Neurosci Rep. 2006 Mar; 6(2):136-43. Acosta MT, Gioia GA, Silva AJ. PMID: 16522267.
    View in: PubMed   Mentions: 35     Fields:    Translation:Humans
  111. Matrix metalloproteinase-9 is required for hippocampal late-phase long-term potentiation and memory. J Neurosci. 2006 Feb 15; 26(7):1923-34. Nagy V, Bozdagi O, Matynia A, Balcerzyk M, Okulski P, Dzwonek J, Costa RM, Silva AJ, Kaczmarek L, Huntley GW. PMID: 16481424; PMCID: PMC4428329.
    View in: PubMed   Mentions: 234     Fields:    Translation:AnimalsCells
  112. Forebrain-specific knockout of B-raf kinase leads to deficits in hippocampal long-term potentiation, learning, and memory. J Neurosci Res. 2006 Jan; 83(1):28-38. Chen AP, Ohno M, Giese KP, Kühn R, Chen RL, Silva AJ. PMID: 16342120.
    View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
  113. The HMG-CoA reductase inhibitor lovastatin reverses the learning and attention deficits in a mouse model of neurofibromatosis type 1. Curr Biol. 2005 Nov 08; 15(21):1961-7. Li W, Cui Y, Kushner SA, Brown RA, Jentsch JD, Frankland PW, Cannon TD, Silva AJ. PMID: 16271875.
    View in: PubMed   Mentions: 179     Fields:    Translation:Animals
  114. Modulation of presynaptic plasticity and learning by the H-ras/extracellular signal-regulated kinase/synapsin I signaling pathway. J Neurosci. 2005 Oct 19; 25(42):9721-34. Kushner SA, Elgersma Y, Murphy GG, Jaarsma D, van Woerden GM, Hojjati MR, Cui Y, LeBoutillier JC, Marrone DF, Choi ES, De Zeeuw CI, Petit TL, Pozzo-Miller L, Silva AJ. PMID: 16237176; PMCID: PMC2802213.
    View in: PubMed   Mentions: 93     Fields:    Translation:HumansAnimalsCells
  115. Notch to remember. Trends Neurosci. 2005 Aug; 28(8):429-35. Costa RM, Drew C, Silva AJ. PMID: 15922461.
    View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
  116. Trace eyeblink conditioning requires the hippocampus but not autophosphorylation of alphaCaMKII in mice. Learn Mem. 2005 May-Jun; 12(3):211-5. Ohno M, Tseng W, Silva AJ, Disterhoft JF. PMID: 15897256.
    View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
  117. Trafficking in emotions. Nat Neurosci. 2005 May; 8(5):548-50. Ehninger D, Matynia A, Silva AJ. PMID: 15856058.
    View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
  118. Increased neuronal excitability, synaptic plasticity, and learning in aged Kvbeta1.1 knockout mice. Curr Biol. 2004 Nov 09; 14(21):1907-15. Murphy GG, Fedorov NB, Giese KP, Ohno M, Friedman E, Chen R, Silva AJ. PMID: 15530391.
    View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
  119. New circuits for old memories: the role of the neocortex in consolidation. Neuron. 2004 Sep 30; 44(1):101-8. Wiltgen BJ, Brown RA, Talton LE, Silva AJ. PMID: 15450163.
    View in: PubMed   Mentions: 119     Fields:    Translation:HumansAnimals
  120. Deletion of the neuron-specific protein delta-catenin leads to severe cognitive and synaptic dysfunction. Curr Biol. 2004 Sep 21; 14(18):1657-63. Israely I, Costa RM, Xie CW, Silva AJ, Kosik KS, Liu X. PMID: 15380068.
    View in: PubMed   Mentions: 80     Fields:    Translation:AnimalsCells
  121. Memory reconsolidation and extinction have distinct temporal and biochemical signatures. J Neurosci. 2004 May 19; 24(20):4787-95. Suzuki A, Josselyn SA, Frankland PW, Masushige S, Silva AJ, Kida S. PMID: 15152039; PMCID: PMC6729467.
    View in: PubMed   Mentions: 446     Fields:    Translation:Animals
  122. The involvement of the anterior cingulate cortex in remote contextual fear memory. Science. 2004 May 07; 304(5672):881-3. Frankland PW, Bontempi B, Talton LE, Kaczmarek L, Silva AJ. PMID: 15131309.
    View in: PubMed   Mentions: 390     Fields:    Translation:AnimalsCells
  123. Molecular and cellular cognition; the unraveling of memory retrieval. Cell. 2004 Apr 02; 117(1):3-4. Brown R, Silva AJ. PMID: 15066276.
    View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
  124. Consolidation of CS and US representations in associative fear conditioning. Hippocampus. 2004; 14(5):557-69. Frankland PW, Josselyn SA, Anagnostaras SG, Kogan JH, Takahashi E, Silva AJ. PMID: 15301434.
    View in: PubMed   Mentions: 59     Fields:    Translation:Animals
  125. The antimetabolite ara-CTP blocks long-term memory of conditioned taste aversion. Learn Mem. 2003 Nov-Dec; 10(6):503-9. Wang J, Ren K, Pérez J, Silva AJ, Peña de Ortiz S. PMID: 14657261; PMCID: PMC305465.
    View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
  126. Learning and memory deficits in Notch mutant mice. Curr Biol. 2003 Aug 05; 13(15):1348-54. Costa RM, Honjo T, Silva AJ. PMID: 12906797.
    View in: PubMed   Mentions: 88     Fields:    Translation:AnimalsCells
  127. MAPK, CREB and zif268 are all required for the consolidation of recognition memory. Philos Trans R Soc Lond B Biol Sci. 2003 Apr 29; 358(1432):805-14. Bozon B, Kelly A, Josselyn SA, Silva AJ, Davis S, Laroche S. PMID: 12740127; PMCID: PMC1693143.
    View in: PubMed   Mentions: 117     Fields:    Translation:AnimalsCells
  128. Pharmacologically regulated induction of silent mutations (PRISM): combined pharmacological and genetic approaches for learning and memory. Neuroscientist. 2003 Apr; 9(2):104-9. Frankland PW, Ohno M, Takahashi E, Chen AR, Costa RM, Kushner SA, Silva AJ. PMID: 12708614.
    View in: PubMed   Mentions: 3     Fields:    Translation:Animals
  129. The RAS effector RIN1 modulates the formation of aversive memories. J Neurosci. 2003 Feb 01; 23(3):748-57. Dhaka A, Costa RM, Hu H, Irvin DK, Patel A, Kornblum HI, Silva AJ, O'Dell TJ, Colicelli J. PMID: 12574403; PMCID: PMC6741936.
    View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
  130. Molecular and cellular cognitive studies of the role of synaptic plasticity in memory. J Neurobiol. 2003 Jan; 54(1):224-37. Silva AJ. PMID: 12486706.
    View in: PubMed   Mentions: 97     Fields:    Translation:AnimalsCells
  131. Selective cognitive dysfunction in acetylcholine M1 muscarinic receptor mutant mice. Nat Neurosci. 2003 Jan; 6(1):51-8. Anagnostaras SG, Murphy GG, Hamilton SE, Mitchell SL, Rahnama NP, Nathanson NM, Silva AJ. PMID: 12483218.
    View in: PubMed   Mentions: 188     Fields:    Translation:Animals
  132. Mouse models of neurofibromatosis type I: bridging the GAP. Trends Mol Med. 2003 Jan; 9(1):19-23. Costa RM, Silva AJ. PMID: 12524206.
    View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
  133. Inhibitory autophosphorylation of CaMKII controls PSD association, plasticity, and learning. Neuron. 2002 Oct 24; 36(3):493-505. Elgersma Y, Fedorov NB, Ikonen S, Choi ES, Elgersma M, Carvalho OM, Giese KP, Silva AJ. PMID: 12408851.
    View in: PubMed   Mentions: 141     Fields:    Translation:AnimalsCells
  134. Autophosphorylation of alphaCaMKII is required for ocular dominance plasticity. Neuron. 2002 Oct 24; 36(3):483-91. Taha S, Hanover JL, Silva AJ, Stryker MP. PMID: 12408850.
    View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
  135. Genetic approaches to molecular and cellular cognition: a focus on LTP and learning and memory. Annu Rev Genet. 2002; 36:687-720. Matynia A, Kushner SA, Silva AJ. PMID: 12429705.
    View in: PubMed   Mentions: 28     Fields:    Translation:Animals
  136. The molecules of forgetfulness. Nature. 2002 Aug 29; 418(6901):929-30. Silva AJ, Josselyn SA. PMID: 12198533.
    View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
  137. Molecular and cellular mechanisms underlying the cognitive deficits associated with neurofibromatosis 1. J Child Neurol. 2002 Aug; 17(8):622-6; discussion 627-9, 646-51. Costa RM, Silva AJ. PMID: 12403561.
    View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimals
  138. A pharmacogenetic inducible approach to the study of NMDA/alphaCaMKII signaling in synaptic plasticity. Curr Biol. 2002 Apr 16; 12(8):654-6. Ohno M, Frankland PW, Silva AJ. PMID: 11967152.
    View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
  139. CREB required for the stability of new and reactivated fear memories. Nat Neurosci. 2002 Apr; 5(4):348-55. Kida S, Josselyn SA, Peña de Ortiz S, Kogan JH, Chevere I, Masushige S, Silva AJ. PMID: 11889468.
    View in: PubMed   Mentions: 261     Fields:    Translation:Animals
  140. Central nervous system myelination in mice with deficient expression of Notch1 receptor. J Neurosci Res. 2002 Feb 01; 67(3):309-20. Givogri MI, Costa RM, Schonmann V, Silva AJ, Campagnoni AT, Bongarzone ER. PMID: 11813235.
    View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
  141. Mechanism for the learning deficits in a mouse model of neurofibromatosis type 1. Nature. 2002 Jan 31; 415(6871):526-30. Costa RM, Federov NB, Kogan JH, Murphy GG, Stern J, Ohno M, Kucherlapati R, Jacks T, Silva AJ. PMID: 11793011.
    View in: PubMed   Mentions: 253     Fields:    Translation:Animals
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